“The amine [serotonin] plays important roles in the regulation of pituitary hormone secretion. It is implicated in promoting prolactin release in response to suckling stimulus, and it affects the secretions of growth hormone, ACTH, TSH, and the gonadotropins.”
Similar to cholesterol causing heart disease and saturated fat clogging your arteries, serotonin's role in depression and anxiety, as portrayed by the mainstream, seems to be completely bogus.
Serotonin's ability to increase ACTH, which increases cortisol, suggests that it precedes many functional models that attempt to "correct" stress related disorders (hair loss, leaky gut, insomnia, elevated cortisol, food intolerances, low testosterone, high estrogen, etc.).
Serotonin = Stress
One of Dr. Peat's central ideas is that estrogen, adrenaline, and serotonin are all part of the "emergency" stress response.
Corroborating Dr. Peat's theories are the works of Hans Selye and Constance R. Martin. In Endocrine Physiology (1985) Martin describe serotonin's role in stress:
While commonly thought of as a neurotransmitter found exclusively in the brain, serotonin is mostly found in the intestine:
Serotonin can be increased several different ways:
Besides being a visionary, Peat is a bona fide nutritional historian. In this interview, Peat recalls the details behind the promotion of serotonin from the "hormone of misery" to the "hormone of happiness."
Serotonin's ability to increase ACTH, which increases cortisol, suggests that it precedes many functional models that attempt to "correct" stress related disorders (hair loss, leaky gut, insomnia, elevated cortisol, food intolerances, low testosterone, high estrogen, etc.).
Serotonin = Stress
One of Dr. Peat's central ideas is that estrogen, adrenaline, and serotonin are all part of the "emergency" stress response.
Corroborating Dr. Peat's theories are the works of Hans Selye and Constance R. Martin. In Endocrine Physiology (1985) Martin describe serotonin's role in stress:
"The amine [serotonin] plays important roles in the regulation of pituitary hormone secretion. It is implicated in promoting prolactin release in response to suckling stimulus, and it affects the secretions of growth hormone, ACTH, TSH, and the gonadotropins." (Martin)
"Serotonin acts centrally to affect renin release, and it promotes ACTH secretion." (Martin)
"Approximately 98% of total serotonin is found outside of the central nervous system. The blood platelets and gastrointestinal tract account for around 95% and serotonin is a component of both central and peripheral mast cells." (Martin)
- Because the largest concentrations of serotonin are found in the intestine, foods that digest poorly or are irritants (gluten, carrageenan) can cause increased levels of serotonin (Peat).
- Serotonin is bound in blood platelets. Platelets "spill" their serotonin when there is too little carbon dioxide in the blood (Martin, Peat).
- Elevated free fatty acids ("burning fat for fuel") generates less CO2 than the oxidation of sugar and can increase the influence of serotonin (Peat).
Besides being a visionary, Peat is a bona fide nutritional historian. In this interview, Peat recalls the details behind the promotion of serotonin from the "hormone of misery" to the "hormone of happiness."
"The misrepresentations about LSD, as a powerful antiserotonin agent, allowed a set of cultural stereotypes about serotonin to be established. Misconceptions about serotonin and melatonin and tryptophan, which are metabolically interrelated, have persisted, and it seems that the drug industry has exploited these mistakes to promote the “new generation” of psychoactive drugs as activators of serotonin responses. If LSD makes people go berserk, as the government claimed, then a product to amplify the effects of serotonin should make people sane."
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