Monday 29 April 2013

"There are many useless Free Testosterone tests" says Dr John - Free Testosterone reference ranges

Dr John - Free Testosterone reference ranges

Thre are many useless Free Testosterone tests.

Read more here:
http://jcem.endojournals.org/cgi/reprint/86/6/2903.pdf
Quote "I know of no other that has been demonstrated
to be so egregiously incorrect."

I am trying to spread the news since I found obout it few moths ago.

There is workaroud, get TotalT, SHBG and Albumin in the same blood draw and calculate your self using:
Free & Bioavailable Testosterone calculator
and
http://www.get-back-on-track.com/en/tools/umrechner.php

Only Quest Diagnostic have correct FreeT, but it also makes it hard to get. On standard ordering form they list the bad one. To get correct one you have to order

Free, Bioavailable, and Total Testosterone.
Testosterone, LC/MS/MS from Quest Diagnostics

When Dr Shippen is adjusting its patients and try a range 100-250 that is for the correct FreeT.

There is 2006 work that discusses better method of calculating to account for new knowledge about SHBG.
-----http://www.atypon-link.com/WDG/doi/pdf/10.1515/JLM.2006.050

It does not help me much, but it have information of FreeT and BAT levels in healthy men,
Table2
10 healthy young men BAT=5.5(nmol/L)
Table 4
10 male control subjects FreeT=199(pmol/L)
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Please add to this topic.